Carragelose® (iota-carrageenan) is free of lambda-carrageenan and has a mean size of more than 1 million Dalton (very large) and it is also free of degraded components. The raw material for the Carragelose® products is tested for the presence of lambda-carrageenan and also the size of the polymer is tested. While lambda carrageenan has been shown to have pro-inflammatory properties, iota and kappa carrageenan have not such a potential. Carrageenan is used in three different subtypes: iota, kappa, and lambda carrageenan that differ in their structure with respect to the number of sulfate groups. There have been reports that carrageenan may induce IBD (Inflammatory Bowel Disease) or colon cancer, mainly based on experiments with rats that have been fed with a diet containing very high concentrations of degraded carrageenan. Overall, the risk of absorbing mercury through Carragelose® is extremely low. Marinomed also had Carragelose® tested at the Fraunhofer Institute for the presence of mercury (and other metals) using optical emission spectrometry with inductively coupled plasma (ICP OES) and mercury could not be detected in the samples. In case of the nasal spray, the intake is almost 10,000 times less than the limit value. Six lozenges a day equal a maximum intake of 60 ng mercury, 200 times less than the limit value. The currently applicable limit for the absorption of organic mercury is 1.6 micrograms per kilogram of body weight and week (= 13 micrograms per day for a person weighing 60 kg). This includes drinking water, food, air and above all amalgam. The PWTI value (provisional tolerable weekly intake) is currently 300 µg/week (1 µg = 1.000 ng) and includes all possible sources through which mercury can be absorbed. In the nasal sprays or throat sprays, the Carragelose® content is around 1.3 mg/day if used 4 times daily and thus the maximum mercury content is 1.3 ng/day. This means that the maximum possible amount of mercury in the Carragelose® lozenges is 10 ng per lozenge. The maximum allowed amount is 1 ng of mercury per mg of Carragelose®. Carragelose® is tested for mercury before it is processed in the finished products.
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